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From 1-Sulfonyl-4-aryl-1,2,3-triazoles to 1-Allenyl-5-aryl-1,2,3-triazoles

Kai Huang, Guorong Sheng, Ping Lu, Yanguang Wang

J Org Chem. 2017 May 19;82(10):5294-5300.

PMID: 28474887

Abstract:

An efficient and highly regioselective synthesis of 1-allenyl-5-aryl-1,2,3-triazoles from 1-sulfonyl-4-aryl-1,2,3-triazoles is disclosed. 1-Sulfonyl-4-aryl-1,2,3-triazoles reacted with propargylic alcohols in the presence of trifluoroboron etherate to furnish 1-allenyl-5-aryl-1,2,3-triazoles. When secondary alcohols were used as substrate, the outcome of the reaction was 1-alkyl-5-aryl-1,2,3-triazoles.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP205383171 1,3,5-Triscarboxyphenylethynylbenzene 1,3,5-Triscarboxyphenylethynylbenzene 205383-17-1 Price
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