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Gallium-catalyzed Reductive Chlorination of Carboxylic Acids With copper(II) Chloride

Norio Sakai, Takumi Nakajima, Shinichiro Yoneda, Takeo Konakahara, Yohei Ogiwara

J Org Chem. 2014 Nov 7;79(21):10619-23.

PMID: 25295703

Abstract:

Described herein is the direct chlorination of carboxylic acids using copper(II) chloride via a gallium(III)-catalyzed reduction in the presence of a hydrosiloxane. During this reductive chlorination, the counteranions of CuCl2 functioned as a chloride source.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP24597124 Gallium(II) chloride Gallium(II) chloride 24597-12-4 Price
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