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Generation of the CF3 Radical From Trifluoromethylsulfonium Triflate and Its Trifluoromethylation of Styrenes

Cheng-Pan Zhang, Zong-Ling Wang, Qing-Yun Chen, Chun-Tao Zhang, Yu-Cheng Gu, Ji-Chang Xiao

Chem Commun (Camb). 2011 Jun 21;47(23):6632-4.

PMID: 21559547

Abstract:

The CF(3) radical was generated from the reaction of S-(trifluoromethyl)diphenylsulfonium triflate with Na(2)S(2)O(4) or HOCH(2)SO(2)Na under suitable conditions without further reduction. Based on this, a method for the synthesis of α-trifluoromethylated ketones has been successfully developed.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP111281120 (4-Phenylthiophenyl)diphenylsulfonium triflate (4-Phenylthiophenyl)diphenylsulfonium triflate 111281-12-0 Price
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