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Guanidinium Iodide-Catalyzed Oxidative α-nitroalkylation of β-ketoamides

Koji Yasui, Takanari Kato, Kohei Kojima, Kazuo Nagasawa

Chem Commun (Camb). 2015 Feb 11;51(12):2290-3.

PMID: 25558483

Abstract:

Oxidative nitroalkylation of β-ketoamides and nitroalkanes, mediated by hypoiodide generated from tert-butyl hydrogen peroxide and a catalytic amount of guanidinium iodide, afforded the corresponding α-nitroalkyl-β-ketoamides in up to 97% yield.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP19227704 Guanidinium iodide Guanidinium iodide 19227-70-4 Price
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