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Gymnemagenin-producing Endophytic Fungus Isolated From a Medicinal Plant Gymnema Sylvestre R.Br

Gymnemagenin-producing Endophytic Fungus Isolated From a Medicinal Plant Gymnema Sylvestre R.Br

Ramalingam Parthasarathy, Muthukrishnan Sathiyabama

Appl Biochem Biotechnol. 2014 Mar;172(6):3141-52.

PMID: 24497046

Abstract:

Gymnema sylvestre is a plant containing the triterpenoid gymnemagenin, which is used in the pharmaceutical industry as an antidiabetic agent. The objective of this study was to determine whether endophytic fungi, isolated from G. sylvestre, produce gymnemagenin. We isolated an endophytic fungal strain from the leaves of G. sylvestre which produces gymnemagenin in the medium. The fungus was identified as Penicillium oxalicum based on morphological and molecular methods. The strain had a component with the same TLC Rf value and HPLC retention time as authentic gymnemagenin. The presence of gymnemagenin was further confirmed by FTIR, UV, and (1)H NMR analyses.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP22467078	Gymnemagenin		22467-07-8	Price

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