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High-yield Conversion of (R)-2-octanol From the Corresponding Racemate by Stereoinversion Using Candida Rugosa

Yao Nie, Yan Xu, Xiao Qing Mu, Yan Tang, Juan Jiang, Zhi Hao Sun

Biotechnol Lett. 2005 Jan;27(1):23-6.

PMID: 15685415

Abstract:

Whole cells of Candida rugosa catalyzed the conversion of (R)-2-octanol from the corresponding racemate with the optical purity of 97% e.e. and yield of 92% in 10 h. The product was formed through a stereoinversion involving enantioselective oxidation and asymmetric reduction with 2-octanone as the intermediate.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP5978701 (R)-(−)-2-Octanol (R)-(−)-2-Octanol 5978-70-1 Price
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