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Highly Photosensitive Poly-Sulfur-Bridged Chetomin Analogues From Chaetomium Cochliodes

Meng-Hua Wang, You-Cai Hu, Bing-Da Sun, Meng Yu, Shu-Bin Niu, Zhe Guo, Xiao-Yan Zhang, Tao Zhang, Gang Ding, Zhong-Mei Zou

Org Lett. 2018 Apr 6;20(7):1806-1809.

PMID: 29537276

Abstract:

The highly photosensitive characteristic of poly-sulfide chetomins was first unveiled, and four new unstable analogues, chetomins A-D (1-4), with significant cytotoxicity were successfully purified in darkness. The visible-light-induced desulfurization and intermolecular disproportionation were revealed to initiate the interconversion of chetomin analogues, which explained the long-recognized puzzle of rarity and instability of chetomin analogues.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP1403367 Chetomin Chetomin 1403-36-7 Price
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