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How Fast Can Thiols Bind to the Gold Nanoparticle Surface?

Amanda Bard, Rebeca Rondon, Daniela T Marquez, Anabel E Lanterna, Juan C Scaiano

Photochem Photobiol. 2018 Nov;94(6):1109-1115.

PMID: 30192996

Abstract:

Kinetics of gold nanoparticle surface modification with thiols can take more than one hour for completion. 7-mercapto-4-methylcoumarin can be used to follow the process by fluorescence spectroscopy and serves as a convenient molecular probe to determine relative kinetics. SERS studies with aromatic thiols further support the slow surface modification kinetics observed by fluorescence spectroscopy. The formation of thiolate bonds is a relatively slow process; we recommend one to two hour wait for thiol binding to be essentially complete, while for disulfides, overnight incubation is suggested.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP137215271 7-Mercapto-4-methylcoumarin 7-Mercapto-4-methylcoumarin 137215-27-1 Price
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