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Human Hepatic Stellate Cell Isolation and Characterization

Human Hepatic Stellate Cell Isolation and Characterization

Linshan Shang, Mojgan Hosseini, Xiao Liu, Tatiana Kisseleva, David Allen Brenner

J Gastroenterol. 2018 Jan;53(1):6-17.

PMID: 29094206

Abstract:

The hepatic stellate cells (HSCs) localize at the space of Disse in the liver and have multiple functions. They are identified as the major contributor to hepatic fibrosis. Significant understanding of HSCs has been achieved using rodent models and isolated murine HSCs; as well as investigating human liver tissues and human HSCs. There is growing interest and need of translating rodent study findings to human HSCs and human liver diseases. However, species-related differences impose challenges on the translational research. In this review, we focus on the current information on human HSCs isolation methods, human HSCs markers, and established human HSC cell lines.

Chemicals Related in the Paper:

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IAR42411332	Ubiquitin-15N human	Price
IAR42412056	TIGAR-TAT human	Price
IAR42413492	PLGF-I human	Price
IAR42414636	SLIT-2-N human	Price
IAR42415005	Lin28-TAT human	Price

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