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Hybrid Cell Line From a Cloned Immunoglobulin-Producing Mouse Myeloma and a Nonproducing Mouse Lymphoma

B Mohit, K Fan

Science. 1971 Jan 8;171(3966):75-7.

PMID: 4099030

Abstract:

A hybrid cell line was established by cell fusion between a cloned Balbic myeloma that is resistant to 8-azaguanine and produces immunoglobulin (gammaG and free kappa chain) and C57BL/6N lymphoma that is resistant to bromo-deoxyuridine and does not produce immunoglobulins. The hybrid cells contained the membrane antigens of both parents; they synthesized free kappa chain; no synthesis of gammaG (gamma(2a)) heavy chain was detected.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP9007834-B γ-Globulins from mouse γ-Globulins from mouse 9007-83-4 Price
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