Home
Resources
Publications
Hydrosilylated Allyl-Silica Hybrid Monolithic Columns

Hydrosilylated Allyl-Silica Hybrid Monolithic Columns

Li Li, Luis A Colón

J Sep Sci. 2009 Aug;32(15-16):2737-46.

PMID: 19603392

Abstract:

Organic-inorganic silica hybrid monolithic columns were synthesized containing an allyl pendant. The ally-monolithic columns were then modified via hydrosilylation reactions to introduce further surface functionalization. The approach was demonstrated by functionalizing allyl-monolytic columns with n-octyl-dimethylsilane (C(8)-DMS) and benzyl-dimethylsilane (benzyl-DMS). Of the surface available ally groups on the hybrid monolith (i.e., 6.79 micromol/m(2)), 31.3% reacted via hydrosilylation, resulting in a C(8) surface coverage of 2.12 micromol/m(2). When using benzyl-DMS, a surface coverage of 1.95 micromol/m(2) was calculated for the benzyl groups. The retentivity of the hybrid monolithic columns increased considerably after the hydrosilylation, as monitored by CLC and CEC. The largest increase in retention was observed with the C(8) modified monolith. The hybrid monolithic columns showed higher hydrolytic stability than monolithic columns prepared by the conventional silanoxane bonding of alkyl chlorosilanes modification. The ally-monolithic column provides a platform for the fabrication of hybrid monoliths that can be conveniently modified by means of hydrosilylation, tailoring the surface of the material. The approach is a promising method to prepare hybrid monolithic columns with versatile stationary phases in a simple and efficient manner.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP1631705	Benzyldimethylsilane		1631-70-5	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: