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Identification of 2 alpha-hydroxy-4-pregnene-3,20-dione in Human Pregnancy Urine

Identification of 2 alpha-hydroxy-4-pregnene-3,20-dione in Human Pregnancy Urine

M Colombier, J L Gachancard-Bouya, R J Bègue, M Prost

J Steroid Biochem Mol Biol. 1992 Feb;41(2):191-6.

PMID: 1543688

Abstract:

2 alpha-Hydroxyprogesterone (2 alpha-hydroxy-4-pregnene-3,20-dione) was identified in human late pregnancy urine by liquid-gel chromatography, GLC and GC-MS. In addition, the following 2-hydroxylated C21 steroids were found and identified as 2 zeta-hydroxy-5 zeta-pregnane-3,20-dione, 2 zeta,20 zeta-dihydroxy-4-pregnen-3-one, 2 alpha,3 alpha-dihydroxy-5 alpha- (and 5 beta)-pregnan-20-one, two isomers of pregnane-2,3,20-triol and 2 zeta,3 zeta,16 zeta-trihydroxy-5 zeta-pregnan-20-one.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR42410391	Pregnanediol-2,3,4,20,21-13C5			Price

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