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Identification of 4,6-dioxoheptanoic Acid (Succinylacetone), 3,5-dioxooctanedioic Acid (Succinylacetoacetate) and 4-Oxo-6-hydroxyheptanoic Acid in the Urine From Patients With Hereditary Tyrosinemia

B Lindblad, G Steen

Biomed Mass Spectrom. 1982 Oct;9(10):419-24.

PMID: 7171740

Abstract:

In the urine from patients with hereditary tyrosinemia, three characteristic compounds have been found. They have been identified as 4,6-dioxoheptanoic acid (succinylacetone), 3,5-dioxooctanedioic acid (succinyl-acetoacetate) and 4-oxo-6-hydroxyheptanoic acid. The identities have been established by mass spectrometry of several derivatives, and by comparison with a synthetic sample of 4,6-dioxoheptanoic acid.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP51568184 4,6-Dioxoheptanoic acid 4,6-Dioxoheptanoic acid 51568-18-4 Price
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