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Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase

Martin Lee, Kevin Rey, Katrina Besler, Christine Wang, Jonathan Choy

Results Probl Cell Differ. 2017;62:181-207.

PMID: 28455710

Abstract:

Nitric oxide (NO) is a bioactive gas that has multiple roles in innate and adaptive immune responses. In macrophages, nitric oxide is produced by inducible nitric oxide synthase upon microbial and cytokine stimulation. It is needed for host defense against pathogens and for immune regulation. This review will summarize the role of NO and iNOS in inflammatory and immune responses and will discuss the regulatory mechanisms that control inducible nitric oxide synthase expression and activity.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP4441127 Trimorpholinophosphine oxide Trimorpholinophosphine oxide 4441-12-7 Price
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