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In-utero Exposure to Nelfinavir-Ethyl Methyl Sulfone

Mira Hleyhel, Stéphanie Goujon, Jeanne Sibiude, Stéphane Blanche, Josiane Warszawski, on behalf the ANRS French Perinatal Cohort study Group

AIDS. 2016 Nov 13;30(17):2729-2730.

PMID: 27662548

Abstract:

Ethyl methyl sulfone contained in nelfinavir between 2007 and 2008 accidentally exposed embryos and fetuses to a powerful mutagen. We report data for 101 HIV-uninfected children exposed in utero included in the French prospective national cohort. The incidence of malformation was similar to that in the cohort as a whole with different drug exposures; no children had developed cancer after 9 years of follow-up.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP594434 Ethyl methyl sulfone Ethyl methyl sulfone 594-43-4 Price
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