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Inactivated Salmonella Enterica Serovar Typhimurium Monophasic Variant (S. Typhimurium 1,4,[5],12:i-) in Sows Is Effective to Control Infection in Piglets Under Field Condition

Inactivated Salmonella Enterica Serovar Typhimurium Monophasic Variant (S. Typhimurium 1,4,[5],12:i-) in Sows Is Effective to Control Infection in Piglets Under Field Condition

J Ruggeri, M Pesciaroli, F Foresti, E Giacomini, M Lazzaro, M C Ossiprandi, A Corradi, G Lombardi, P Pasquali, G L Alborali

Vet Microbiol. 2015 Oct 22;180(1-2):82-9.

PMID: 26260858

Abstract:

The monophasic variant of Salmonella enterica serovar Typhimurium, namely Salmonella 1,4,[5],12:i-, has been increasingly responsible for foodborne human cases of disease and is most frequently detected in pork, since the variant is widely spread in pig farms. The aim of this study was to assess the efficacy of an autologous vaccine in decreasing the prevalence of Salmonella 1,4,[5],12:i-, in pigs. The trial was performed in a multisite pig production system of Northern Italy. The autogenous vaccine was prepared from the Salmonella 1,4,[5],12:i- strain isolated from the clinical case occurring in the Farm. Different immunization protocols were applied, ranging from interventions only in sows or piglets, or both. Microbiological analysis was performed to assess faecal shedding in sows and their offspring from birth till end of the production cycle and organ colonization of slaughtered pigs. Body weight of pigs was recorded at different time-points. Humoral immune response was evaluated in serum samples of sows and piglets. S. Typhimurium 1,4,[5],12:i- determines reduction of animal growth and farm production, furthermore, contamination of carcasses at the slaughterhouse. The load of bacteria entering into the food processing chain is differently influenced by the regimen of administration of inactivated vaccine. In particular, a combined vaccination of sows and their offspring was able to improve the weight gain of growing pigs, to limit Salmonella colonization of organs and to reduce the number of carrier pigs, and hence lowering the risk of introducing Salmonella organisms in the slaughter process.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR42410684	Inactivated Salmonella enterica			Price

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