Home
Resources
Publications
Influence of Silica Surface Coating on Operated Photodynamic Therapy Property of Yb

Influence of Silica Surface Coating on Operated Photodynamic Therapy Property of Yb

Yuemei Li, Rui Wang, Yanling Xu, Wei Zheng, Yongmei Li

Inorg Chem. 2018 Jul 2;57(13):8012-8018.

PMID: 29905468

Abstract:

Photodynamic therapy (PDT) is a noninvasive therapeutic technique. Upconversion nanoparticles (UCNPs) hold promise for photodynamic therapy (PDT). UCNPs with antistokes emission can improve the tissue penetration depth of PDT. However, the low upconversion efficiency poses a strong limit on further development of PDT. The core/shell structure Yb/Tm/GZO@SiO2 UCNPs are designed, which can form multistep cascade energy transfer from sillica shell to core Ga-doped Yb/Tm/ZnO. Compared with Yb/Tm/ZnO upconversion (UC) semiconductor nanoparticles (SNCs), the multistep cascade energy transfer process provides about seven times enhanced UCL emission. For the UCL-optimized core/shell upconversion SNCs of Yb7/Tm0.5/G3ZO@mSiO2, the Yb3+ energy transfer efficiency is determined to be as high as ∼81% under 980 nm laser excitation. In addition, the Yb7/Tm0.5/G3ZO@mSiO2 core/shell UCNPs have an excellent PDT treatment for Hela cells under 980 nm laser excitation.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP12036441	Thulium(III) oxide		12036-44-1	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: