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Inhibition of Cutaneous and Mucosal Allergy With Phenyltoloxamine

Inhibition of Cutaneous and Mucosal Allergy With Phenyltoloxamine

C J Falliers, M A Redding, C P Katsampes

Ann Allergy. 1978 Sep;41(3):140-4.

PMID: 28684

Abstract:

A dose-and-time related-effect of oral phenyltoloxamine citrate, a Class I, H1 antihistamine compound, has been demonstrated against allergen-induced wheal-and-erythema skin reactions among 10 adults with a diagnosis of allergic rhinitis and seasonal pollinosis. Clinical improvement in the existing symptoms of rhinorrhea, nasal obstruction, pruritus and sneezing, showed a significant correlation with the inhibition of reagin-mediated skin reactivity caused by phenytoloxamine. No adverse side effects were observed. It can be concluded that oral phenyltoloxamine citrate possesses antihistaminic properties and a range of safety which make it a useful agent for the symptomatic management of upper respiratory allergy.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP75859722	Phenyltoloxamine Related Compound A		75859-72-2	Price

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