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Inhibition of Lipid Peroxidation and the Active Oxygen Radical Scavenging Effect of Anthocyanin Pigments Isolated From Phaseolus Vulgaris L

T Tsuda, K Shiga, K Ohshima, S Kawakishi, T Osawa

Biochem Pharmacol. 1996 Oct 11;52(7):1033-9.

PMID: 8831722

Abstract:

No attention has been paid to anthocyanin pigments from the viewpoint of inhibitors of lipid peroxidation and scavengers of active oxygen radicals; therefore, we investigated the antioxidative, radical scavenging, and inhibitory effects on lipid peroxidation by UV light irradiation of three anthocyanin pigments, pelargonidin 3-O-beta-D-glucoside (P3G), cyanidin 3-O-beta-D-glucoside (C3G), and delphinidin 3-O-beta-D-glucoside (D3G), isolated from the Phaseolus vulgaris L. seed coat, and their aglycons, pelargonidin chloride (Pel), cyanidin chloride (Cy), and delphinidin chloride (Del). All pigments had strong antioxidative activity in a liposomal system and reduced the formation of malondialdehyde by UVB irradiation. On the other hand, the extent of antioxidative activity in a rat liver microsomal system and the scavenging effect of hydroxyl radicals (-OH) and superoxide anion radicals (O2-) were influenced by their own structures.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP6906383-B Delphinidin 3-O-β-D-glucoside chloride Delphinidin 3-O-β-D-glucoside chloride 6906-38-3 Price
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