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Insensitivity of Factor V and Factor Va to Diisopropylfluorophosphate and Antithrombin III

S Bartlett, S S Bajwa, P Latson, S Y Weinstein, D J Hanahan

Biochim Biophys Acta. 1978 Jun 9;524(2):485-90.

PMID: 667083

Abstract:

Bovine plasma Factor V and Factor Va, the latter prepared by thrombin or venom activator action on Factor V, are not inactivated by diisopropylfluorophosphate or antithrombin III nor do they form identifiable complexes with either of these reagents. On the basis of these data, it is concluded that bovine Factor V and Factor Va are not serine proteases.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP90170802-A Antithrombin III from bovine plasma Antithrombin III from bovine plasma 90170-80-2 Price
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