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Interleukin-7 and Immunosenescence

Interleukin-7 and Immunosenescence

Vanloan Nguyen, Andrew Mendelsohn, James W Larrick

J Immunol Res. 2017;2017:4807853.

PMID: 28484723

Abstract:

The age of an individual is an important, independent risk factor for many of the most common diseases afflicting modern societies. Interleukin-7 (IL-7) plays a central, critical role in the homeostasis of the immune system. Recent studies support a critical role for IL-7 in the maintenance of a vigorous healthspan. We describe the role of IL-7 and its receptor in immunosenescence, the aging of the immune system. An understanding of the role that IL-7 plays in aging may permit parsimonious preventative or therapeutic solutions for diverse conditions. Perhaps IL-7 might be used to "tune" the immune system to optimize human healthspan and longevity.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR4248612	Interleukin-7 human			Price

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