Home
Resources
Publications
[Investigation of Variations of Components in Euphorbia Pekinensis Root and Its Processed Products Based on Plant Metabolomics]

[Investigation of Variations of Components in Euphorbia Pekinensis Root and Its Processed Products Based on Plant Metabolomics]

Yan Zeng, Peng-yi Hou, Xiao-hui Chen

Zhong Yao Cai. 2016 Mar;39(3):530-3.

PMID: 30088875

Abstract:

Objective:
An ultra-performance liquid chromatography coupled with mass spectrometry( UPLC-MS) based on plant metabonomics method was proposed and developed for the investigation of variations of components in Euphorbia pekinensis root after herb-processing procedure.
Methods:
The samples were separated on an Agilent XDB C8column( 150 mm × 4. 6 mm,5 μm) using a mobile phase composed of 0. 1% formic acid in acetonitrile and 0. 1% formic acid in water under gradient elution. Analysis was performed with electrospray ionization( ESI) interface in negative ion mode within the m / z range of 100 ~ 900. The data were subjected to principal component analysis( PCA).
Results:
Seven components were screened out which could be considered as potential chemical markers to discriminate Euphorbia pekinensis root from its processed products. Six of the chemical markers were identified as 3,3'-di-O-methylellagic acid-4'-O-β-D-xylopyranoside,3,3'-di-O-methyl ellagic acid,(-)-( 1S)-15-hydroxy-18-carboxycembrene,ellagic acid,brevifolincarboxylic acid and gallic acid.
Conclusion:
The method has been successfully applied in distinguishing Euphorbia pekinensis root from its processed products,which predicts the potential substances contributed to the toxicity reducing effect of traditional processing procedure on the herb.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP18490954	Brevifolincarboxylic acid		18490-95-4	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: