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Iodide-Mediated or Iodide-Catalyzed Demethylation and Friedel-Crafts C-H Borylative Cyclization Leading to Thiophene-Fused 1,2-Oxaborine Derivatives

Keisuke Shigemori, Momoka Watanabe, Julie Kong, Koichi Mitsudo, Atsushi Wakamiya, Hiroki Mandai, Seiji Suga

Org Lett. 2019 Apr 5;21(7):2171-2175.

PMID: 30843697

Abstract:

The first synthesis of dithieno-1,2-oxaborine derivatives was achieved via iodide-mediated or iodide-catalyzed demethylation of 3-methoxy-2,2'-bithiophene and subsequent C-H borylation. A wide variety of thiophene-fused oxaborines could be synthesized by the procedure.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
LS7932266 2-Acetoxyphenylzinc iodide 2-Acetoxyphenylzinc iodide Price
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