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Is a 1,4-Alkyl Shift Involved in the Biosynthesis of Ledol and Viridiflorol?

Young J Hong, Dean J Tantillo

J Org Chem. 2017 Apr 7;82(7):3957-3959.

PMID: 28277661

Abstract:

Results from density functional theory computations indicate that a 1,4-alkyl shift proposed as part of the carbocation cyclization/rearrangement leading to ledol, viridiflorol, and related sesquiterpenes is not energetically viable. Instead, a previously proposed mechanism that avoids such a shift is greatly preferred.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP552023 Viridiflorol Viridiflorol 552-02-3 Price
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