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Isolation and Genomic Analysis of 11-aminoundecanoic Acid-Degrading Bacterium

Jocelyn Gatz-Schrupp, Peter Deckard, Benjamin Hufford, Steven Ly, Peter Tupa, Hisako Masuda

J Genomics. 2020 Jan 25;8:16-20.

PMID: 32064005

Abstract:

Nylon 11 is a polymer synthesized from 11-aminoundecanoic acid, and widely used in commercial manufacturing. In this study, we describe the isolation of the first organism capable of metabolizing 11-aminoundecanoic acid from nylon 11 enrichment culture. The strain shows rapid growth on 11-aminoundecanoic acid as a sole source of carbon, nitrogen, and energy. Furthermore, the genome sequence of strain JG-B was deciphered and shown to belong to genus Pseudomonas. Many genes encoding putative extracellular hydrolases, as well as homologues of nylon 6 hydrolases (NylB and NylA) were identified, suggesting the metabolic versatility and possibility that this organism could also depolymerase nylon 11 polymers.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP25035045 Nylon 11 Nylon 11 25035-04-5 Price
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