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Isolation of Camelliaside C From "Tea Seed Cake" and Inhibitory Effects of Its Derivatives on Arachidonate 5-lipoxygenase

T Sekine, Y Arai, F Ikegami, Y Fujii, S Shindo, T Yanagisawa, Y Ishida, S Okonogi, I Murakoshi

Chem Pharm Bull (Tokyo). 1993 Jun;41(6):1185-7.

PMID: 8370116

Abstract:

A new flavonol glycoside, camelliaside C, was isolated from "tea seed cake" prepared from the defatted seeds of Camellia sinensis O. Kuntze. The structure was determined as kaempferol 3-O-beta-D-galactopyranosyl-(1-->2)-beta-D-glucopyranoside by spectroscopic methods (FAB-MS, UV, IR, 1H- and 13C-NMR) and the enzymatic transformation of camelliaside C to astragalin. Camelliaside C showed an inhibitory effect on the arachidonate 5-lipoxygenase of RBL-1 cells (IC50:1.4 x 10(-4)M) as did camelliaside A and B isolated from the same product.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP135095522 Camelliaside A Camelliaside A 135095-52-2 Price
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