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K-252a, a Potent Inhibitor of Protein Kinase C From Microbial Origin

H Kase, K Iwahashi, Y Matsuda

J Antibiot (Tokyo). 1986 Aug;39(8):1059-65.

PMID: 3759657

Abstract:

K-252a, a metabolite isolated from the culture broth of Nocardiopsis sp. K-252a, was found to exhibit an extremely potent inhibitory activity on protein kinase C. The IC50 value was 32.9 nM.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP99533809-A K-252a K-252a 99533-80-9 Price
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