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Ketorolac Tromethamine 0.4% as a Treatment for Allergic Conjuctivitis

Ketorolac Tromethamine 0.4% as a Treatment for Allergic Conjuctivitis

Barry A Schechter

Expert Opin Drug Metab Toxicol. 2008 Apr;4(4):507-11.

PMID: 18433352

Abstract:

Background:
Acular LS (ketorolac tromethamine 0.4%) ophthalmic solution, a reformulation of the original Acular (ketorolac tromethamine 0.5%), is indicated for the reduction of ocular pain and burning/stinging following corneal refractive surgery.
Objective:
This manuscript will review the off-label application of this topical NSAID medication as a treatment for allergic conjunctivitis.
Methods:
An extensive MedLine search was undertaken to evaluate data on the use of ketorolac for allergic conjunctivitis. Data on both human and animal data were reviewed.
Results/conclusions:
Studies have demonstrated that ketorolac 0.4% has equivalent efficacy to ketorolac 0.5%. Several studies have demonstrated that ketorolac effectively treats allergic conjunctivitis. Ketorolac 0.4% is effective when used as either monotherapy or as adjunct therapy to steroids.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP74103074	Ketorolac Tromethamine		74103-07-4	Price

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