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Kinetics of Inhibition of Penaeus Penicillatus Acid Phosphatase by Bromoacetic Acid

Q X Chen, S L Chen, H M Zhou

Biochem Mol Biol Int. 1998 Oct;46(2):215-23.

PMID: 9801789

Abstract:

The kinetics of inhibition of penaeus penicillatus acid phosphatase by bromoacetic acid has been studied. The results show that inhibition of the enzyme by bromoacetic acid is a slow, reversible reaction. The microscopic rate constants for the reaction of inhibitor with the enzyme were determined. The presence of the substrate offers marked protection of this enzyme against inhibition by bromoacetic acid. The above results suggest that the histidine residue is essential for activity and are situated at the active site of the enzyme.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP52947009 Bromoacetic acid-13C2 Bromoacetic acid-13C2 52947-00-9 Price
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