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Label-free Liquid Crystal Biosensor for Cecropin B Detection

Label-free Liquid Crystal Biosensor for Cecropin B Detection

Jiao Zhang, Xiuxia Su, Dong Yang, Chonglin Luan

Talanta. 2018 Aug 15;186:60-64.

PMID: 29784409

Abstract:

A label-free liquid crystal (LC) biosensor based on orientation changes of LC molecules was reported for the detection of cecropin B. The homeotropic-to-tilted alignment transition of LC molecules, induced by the specific binding event between cecropin B and anti-cecropin B antibody immobilized via glutaraldehyde, could result in obvious change of the optical appearance from a dark to a bright response and as a result, the detection limit of cecropin B was as low as 50 ng/mL. The average gray-scale intensities (GIs) of optical appearances were calculated to quantitatively analyse cecropin B concentrations. This study offers a simple, highly sensitive and specific, lable-free method for cecropin B detection.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP80451054	Cecropin B		80451-05-4	Price

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