0

Lanthanide or Transition Metal Ions-Mediated Cleavage of DNA by Hydroxamic Acid Derivative

S Hashimoto, Y Nakamura

Nucleic Acids Symp Ser. 1995;(34):17-8.

PMID: 8841530

Abstract:

N-[5-(hydroxylaminocarbonyl)pentyl]phenanthridium chloride 1 has been shown to induce cleavage of ColE1 DNA in the presence of transition (ferrous, ferric and vanadyl) or lanthanide(III) (lutetium, thulium and europium) metal ions. The addition of free radical scavengers inhibits the former reaction, but does not the latter case.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP10099668 Lutetium(III) chloride Lutetium(III) chloride 10099-66-8 Price
AP13537183 Thulium(III) chloride Thulium(III) chloride 13537-18-3 Price
qrcode