0

Laurus Nobilis: Composition of Essential Oil and Its Biological Activities

Lucia Caputo, Filomena Nazzaro, Lucéia Fatima Souza, Luigi Aliberti, Laura De Martino, Florinda Fratianni, Raffaele Coppola, Vincenzo De Feo

Molecules. 2017 Jun 3;22(6):930.

PMID: 28587201

Abstract:

Laurus nobilis is native to the southern Mediterranean region and cultivated mainly in Europe and the USA as an ornamental and medicinal plant. The chemical composition of the essential oil (EO) from leaves of L. nobilis, collected in Southern Italy, was studied by GC and GC-MS. In all, 55 compounds were identified, accounting for 91.6% of the total oil. 1,8-Cineole (31.9%), sabinene (12.2%), and linalool (10.2%) were the main components. Antimicrobial and antifungal activities of EO and 1,8-cineole were determined in vitro. The cytotoxicity of the EO was evaluated against SH-SY5Y cell line, as well as the influence of the EO on the expression of adenylate cyclase 1 (ADCY1), suggesting possible oil effects on the Central Nervous System.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP3387415 Sabinene Sabinene 3387-41-5 Price
qrcode