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Leptomycins A and B, New Antifungal Antibiotics. I. Taxonomy of the Producing Strain and Their Fermentation, Purification and Characterization

T Hamamoto, S Gunji, H Tsuji, T Beppu

J Antibiot (Tokyo). 1983 Jun;36(6):639-45.

PMID: 6874585

Abstract:

A strain of Streptomyces was found to produce new antifungal antibiotics. The active compounds were purified and separated into two substances named leptomycin A and B by high performance liquid chromatography. The molecular formulae of leptomycins A and B are C32H46O6 and C33H48O6 respectively, and physicochemical and biological properties of them are very similar to each other. Leptomycins A and B exhibit strong inhibitory activity against Schizosaccharomyces and Mucor.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP87081365 Leptomycin A Leptomycin A 87081-36-5 Price
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