0

Macromolecular Prodrugs. VIII. Synthesis of Polymer-Gemfibrozil Conjugates

M Lovrek, B Zorc, B Boneschans, I Butula

Int J Pharm. 2000 Apr 25;200(1):59-66.

PMID: 10845686

Abstract:

Gemfibrozil is covalently linked to two similar polymers: poly[alpha,beta-(N-2-hydroxyethyl-DL-aspartamide)] and poly[alpha,beta-(N-3-hydroxypropyl-DL-aspartamide)]. The synthesised polymer drug conjugates differ in average molecular mass, type of covalent bonding, length of spacer, drug-loading and solubility.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP137629324 Poly (α,β-[N-(3-hydroxypropyl)-DL-aspartamide]) Poly (α,β-[N-(3-hydroxypropyl)-DL-aspartamide]) 137629-32-4 Price
qrcode