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Menthalactone, a New Analgesic From Mentha Cordifolia Opiz. Leaves

Menthalactone, a New Analgesic From Mentha Cordifolia Opiz. Leaves

Irene M Villaseñor, Arlyn C Sanchez

Z Naturforsch C J Biosci. Nov-Dec 2009;64(11-12):809-12.

PMID: 20158150

Abstract:

* Author for correspondence and reprint requests Z. Naturforsch. 64c, 809-812 (2009); received May 7/July 23, 2009 Menthalactone, a new long-chain alkene with a bicyclic lactone moiety, was isolated as an analgesic constituent from the leaves of Mentha cordifolia Opiz. At a dosage of 100 mg/ kg mouse, it decreased the number of squirms induced by acetic acid by 67.3%. Statistical analysis using Kruskall Wallis one-way analysis of variance by ranks showed that menthalac-tone is different from the solvent control at alpha = 0.01 and approximates the analgesic activity of mefenamic acid at 0.001 level of significance.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP13341725	Menthalactone		13341-72-5	Price

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