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Mesenchymal Stem Cells Improve Healing of Diabetic Foot Ulcer

Yue Cao, Xiaokun Gang, Chenglin Sun, Guixia Wang

J Diabetes Res. 2017;2017:9328347.

PMID: 28386568

Abstract:

Mesenchymal stem cells (MSCs), an ideal cell source for regenerative therapy with no ethical issues, play an important role in diabetic foot ulcer (DFU). Growing evidence has demonstrated that MSCs transplantation can accelerate wound closure, ameliorate clinical parameters, and avoid amputation. In this review, we clarify the mechanism of preclinical studies, as well as safety and efficacy of clinical trials in the treatment of DFU. Bone marrow-derived mesenchymal stem cells (BM-MSCs), compared with MSCs derived from other tissues, may be a suitable cell type that can provide easy, effective, and cost-efficient transplantation to treat DFU and protect patients from amputation.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP178402363 DFU DFU 178402-36-3 Price
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