Home
Resources
Publications
Mesoporous Silica Nanoparticles for Drug and Gene Delivery

Mesoporous Silica Nanoparticles for Drug and Gene Delivery

Yixian Zhou, Guilan Quan, Qiaoli Wu, Xiaoxu Zhang, Boyi Niu, Biyuan Wu, Ying Huang, Xin Pan, Chuanbin Wu

Acta Pharm Sin B. 2018 Mar;8(2):165-177.

PMID: 29719777

Abstract:

Mesoporous silica nanoparticles (MSNs) are attracting increasing interest for potential biomedical applications. With tailored mesoporous structure, huge surface area and pore volume, selective surface functionality, as well as morphology control, MSNs exhibit high loading capacity for therapeutic agents and controlled release properties if modified with stimuli-responsive groups, polymers or proteins. In this review article, the applications of MSNs in pharmaceutics to improve drug bioavailability, reduce drug toxicity, and deliver with cellular targetability are summarized. Particularly, the exciting progress in the development of MSNs-based effective delivery systems for poorly soluble drugs, anticancer agents, and therapeutic genes are highlighted.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP41051803	[3-(Diethylamino)propyl]trimethoxysilane		41051-80-3	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: