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Metal Complexes as Self-Indicating Titrants for Acid-Base Reactions in Chloroform

Metal Complexes as Self-Indicating Titrants for Acid-Base Reactions in Chloroform

Antonino Giannetto, Massimiliano Cordaro, Sebastiano Campagna, Santo Lanza

Inorg Chem. 2018 Feb 19;57(4):2175-2183.

PMID: 29394056

Abstract:

The paper reports an unprecedented spectrophotometric determination of amines in chloroform, in which amines are not transformed into colored derivatives. This result has been achieved by exploiting the acid-base properties of the tight-ion-paired metal complexes [(HR2DTO)Pt(H2R2DTO)][Cl], which are able to donate a HCl molecule to an amine, giving rise to an ammonium salt and to the neutral complexes [(HR2DTO)2Pt]. The circumstance that [(HR2DTO)Pt(H2R2DTO)][Cl] and [(HR2DTO)2Pt] species show different absorptions in the visible region of the electromagnetic spectrum enables the aforementioned platinum complexes to behave as self-indicating titrants in the spectrophotometric determination of aliphatic amines, which are known to be UV-vis transparent. The new method has been tested by determining a series of fatty amines in the bulk and gave excellent results. The limits of applicability of this method (pKa > 4) were found by testing a series of benzodiazepines.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
TIT9307	Titrant 2			Price

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