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Metformin: A Hopeful Promise in Aging Research

Metformin: A Hopeful Promise in Aging Research

Marta G Novelle, Ahmed Ali, Carlos Diéguez, Michel Bernier, Rafael de Cabo

Cold Spring Harb Perspect Med. 2016 Mar 1;6(3):a025932.

PMID: 26931809

Abstract:

Even though the inevitable process of aging by itself cannot be considered a disease, it is directly linked to life span and is the driving force behind all age-related diseases. It is an undisputable fact that age-associated diseases are among the leading causes of death in the world, primarily in industrialized countries. During the last several years, an intensive search of antiaging treatments has led to the discovery of a variety of drugs that promote health span and/or life extension. The biguanide compound metformin is widely used for treating people with type 2 diabetes and appears to show protection against cancer, inflammation, and age-related pathologies. Here, we summarize the recent developments about metformin use in translational aging research and discuss its role as a potential geroprotector.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP461585-B	Metformin Related Compound A		461-58-5	Price

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