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Micelle-Encapsulated Fluorescent Probe: Chemoselective and Enantioselective Recognition of Lysine in Aqueous Solution

Gengyu Du, Lin Pu

Org Lett. 2019 Jun 21;21(12):4777-4781.

PMID: 31184163

Abstract:

A diblock copolymer, poly(ethylene glycol) methyl ether- block-poly(l-lactide), is used to solubilize 3,3'-diformylBINOL ( S)-1 in water to make the micelle-encapsulated fluorescent probe M L- S1. It was found that M L- S1 was able to recognize d-lysine chemoselectively as well as enantioselectively among 19 amino acids and their enantiomers in carbonate buffer. The enantioselective fluorescence enhancement ratio [ef = ( ID - I0)/( ID - I0) = Δ ID/Δ IL] up to 6.6 was observed for the response of M L- S1+Zn(II) toward lysine.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
LS74301 Poly(L-lactide)-block-poly(ethylene glycol)methyl ether Poly(L-lactide)-block-poly(ethylene glycol)methyl ether Price
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