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MItomycin C, methyl-CCNU and 5-fluorouracil in the Treatment of Metastatic Colorectal Carcinoma

P D Bonomi, G Chandra, A H Rossof, D Klaassen

Cancer Chemother Pharmacol. 1980;5(1):39-42.

PMID: 7006846

Abstract:

The combination of mitomycin C, methyl-CCNU and 5-fluorouracil produced no objective tumor regressions in 25 evaluable patients with metastatic colorectal carcinoma. Patients who achieved stable disease survived significantly longer than patients who had progressive disease. This difference appeared to be more probably related to pre-treatment characteristics of the patients than caused by treatment. Serial CEA determinations revealed a parallel relationship with tumor behavior in 17 of 19 patients.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP2387237 Lomustine Related Compound C Lomustine Related Compound C 2387-23-7 Price
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