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Modification of the Ceramic Implant Surfaces From Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study

Modification of the Ceramic Implant Surfaces From Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study

Anna I Kozelskaya, Evgeny N Bolbasov, Alexey S Golovkin, Alexander I Mishanin, Alice N Viknianshchuk, Evgeny V Shesterikov, Аndrey Ashrafov, Vadim A Novikov, Alexander Y Fedotkin, Igor A Khlusov, Sergey I Tverdokhlebov

Materials (Basel). 2018 Oct 11;11(10):1949.

PMID: 30314394

Abstract:

In this study, thin calcium phosphate (Ca-P) coatings were deposited on zirconia substrates by radiofrequency (RF) magnetron sputtering using different calcium phosphate targets (calcium phosphate tribasic (CPT), hydroxyapatite (HA), calcium phosphate monobasic, calcium phosphate dibasic dehydrate (DCPD) and calcium pyrophosphate (CPP) powders). The sputtering of calcium phosphate monobasic and DCPD powders was carried out without an inert gas in the self-sustaining plasma mode. The physico-chemical, mechanical and biological properties of the coatings were investigated. Cell adhesion on the coatings was examined using mesenchymal stem cells (MSCs). The CPT coating exhibited the best cell adherence among all the samples, including the uncoated zirconia substrate. The cells were spread uniformly over the surfaces of all samples.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP12167747-B	Calcium phosphate tribasic		12167-74-7	Price

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