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Molindone Hydrochloride Treatment of Hospitalized Children With Conduct Disorder

Molindone Hydrochloride Treatment of Hospitalized Children With Conduct Disorder

L L Greenhill, M Solomon, R Pleak, P Ambrosini

J Clin Psychiatry. 1985 Aug;46(8 Pt 2):20-5.

PMID: 3894338

Abstract:

Treatment-emergent symptoms and behavioral changes were assessed during an 8-week double-blind study comparing molindone and thioridazine in 31 aggressive hospitalized children (ages 6-11). Molindone was found to be as effective as thioridazine in this sample. Adverse effects differed (nonsignificantly) for the two groups, with more sedation in the thioridazine-treated children. Clinical records from 6 adolescent inpatients treated with molindone were reviewed as a comparison group. Molindone is a relatively safe neuroleptic for child and adolescent inpatients because of its short half-life and minimal prolonged tissue accumulation. Additional studies on different child populations are necessary before the proper indications for molindone usage in the pediatric group can be established.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP15622658	Molindone hydrochloride		15622-65-8	Price

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