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Mortality in Patients With Endogenous Cushing's Syndrome

Mortality in Patients With Endogenous Cushing's Syndrome

Pedram Javanmard, Daisy Duan, Eliza B Geer

Endocrinol Metab Clin North Am. 2018 Jun;47(2):313-333.

PMID: 29754634

Abstract:

Cushing's syndrome is associated with increased morbidity and mortality. Cardiovascular events, sepsis, and thromboembolism are the leading causes of mortality. Patient's with Cushing's due to a pituitary adenoma and those with Cushing's due to benign adrenal adenoma have relatively good survival outcomes often mirroring that of the general population. Persistent or recurrent disease is associated with high mortality risk. Ectopic Cushing's syndrome and Cushing's due to adrenocortical carcinoma confer the highest mortality risk among Cushing's etiologies. Prompt diagnosis and treatment, and specific monitoring for and treatment of associated comorbidities are essential to decrease the burden of mortality from Cushing's.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP1052236868	(S)-5-Allyl-2-oxabicyclo[3.3.0]oct-8-ene		1052236-86-8	Price
AP74046074	S(+)-γ-Vigabatrin		74046-07-4	Price

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