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New Dammarane-type Saponins from Gynostemma pentaphyllum

Po-Yen Chen, Chih-Chao Chang, Hui-Chi Huang, Li-Jie Zhang, Chia-Ching Liaw, Yu-Chi Lin, Nham-Linh Nguyen, Thanh-Hoa Vo, Yung-Yi Cheng, Susan L Morris-Natschke, Kuo-Hsiung Lee, Yao-Haur Kuo

Molecules. 2019 Apr 8;24(7):1375.

PMID: 30965662

Abstract:

Six new dammarane-type saponins, gypenosides CP1-6 (16), along with 19 known compounds 7⁻25, were isolated and characterized from the aerial parts of Gynostemma pentaphyllum. Among these compounds, eight dammarane-type saponins, 2, 5, 6, 7, 11, 12, 13, and 15, exhibited the greatest antiproliferative effects against two human tumor cell lines (A549 and HepG2).

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
IAR424665 Phalloidin-Atto 725 Phalloidin-Atto 725 Price
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