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New Possible Chelating Agents of Clinical Interest for iron(III): 2-hydroxynicotinic Acid and 3-hydroxypicolinic Acid. A Thermodynamic Study

V B Di Marco, A Tapparo, G G Bombi

Ann Chim. Sep-Oct 2001;91(9-10):595-603.

PMID: 11770159

Abstract:

The formation of complexes between iron(III) and two ligands of possible relevance to chelation therapy, 2-hydroxynicotinic acid and 3-hydroxypicolinic acid, in aqueous 0.6 m (Na)Cl at 25 degrees C, has been investigated by means of potentiometric titrations and UV measurements. In both cases several mononuclear complexes and their deprotonation products are formed.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP874248 3-Hydroxypicolinic acid 3-Hydroxypicolinic acid 874-24-8 Price
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