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Nicotinamide for Skin Cancer Chemoprevention

Diona L Damian

Australas J Dermatol. 2017 Aug;58(3):174-180.

PMID: 28321860

Abstract:

Nicotinamide (vitamin B3 ) has a range of photoprotective effects in vitro and in vivo; it enhances DNA repair, reduces UV radiation-induced suppression of skin immune responses, modulates inflammatory cytokine production and skin barrier function and restores cellular energy levels after UV exposure. Pharmacological doses of nicotinamide have been shown to reduce actinic keratoses and nonmelanoma skin cancer incidence in high-risk individuals, making this a nontoxic and accessible option for skin cancer chemoprevention in this population.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP98920-B Niacinamide Niacinamide 98-92-0 Price
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