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Nitric Oxide Donor NOC-5 Increases XIAP and Aven Level in Jurkat Cells

Nitric Oxide Donor NOC-5 Increases XIAP and Aven Level in Jurkat Cells

Elena G Starikova, L A Tashireva, V V Novitsky, N V Ryazantseva

Cell Biol Int. 2014 Jul;38(7):799-802.

PMID: 24677341

Abstract:

Mitochondrial permeabilisation after NO donor application did not activate caspase-9. We have studied the X-linked apoptosis inhibitor (XIAP) and Aven protein content in NO-treated Jurkat cells. The level of both proteins increased in NO-treated cells. Thus the increase in XIAP and Aven content could be the cause of the lack of caspase-9 activity after mitochondrial permeabilisation in NO-treated Jurkat cells.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP146724825	NOC-5		146724-82-5	Price

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