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Noninvasive Three-Dimensional Cardiac Activation Imaging on a Rabbit Model

Noninvasive Three-Dimensional Cardiac Activation Imaging on a Rabbit Model

Chengzong Han, Chenguang Liu, Steven Pogwizd, Bin He

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:3271-3.

PMID: 19964067

Abstract:

Three-dimensional cardiac activation imaging (3-DCAI) aims at imaging the activation sequence throughout the 3-D myocardium. In the present study, the performance of 3-DCAI was validated through both in vivo animal experiments and computer simulations under a pacing protocol. The non-invasively imaged activation sequence from body surface potential maps (BSPMs) was quantitatively compared with the measured activation sequence obtained from the simultaneous intramural recording using a 3-D intra-cardiac mapping technique in a rabbit model. In addition, computer simulations were conducted to provide further assessment of the performance of the 3-DCAI algorithm in a realistic-geometry rabbit heart-torso model. The encouraging results suggest that 3-DCAI can non-invasively image the activation sequence and localize the origin of activation with good accuracy.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP299165927	DCAI		299165-92-7	Price

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