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Novel Axially Carborane-Cage Substituted Silicon Phthalocyanine Photosensitizer; Synthesis, Characterization and Photophysicochemical Properties

Göknur Yaşa Atmaca, Cemil Dizman, Tarık Eren, Ali Erdoğmuş

Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 25;137:244-9.

PMID: 25222320

Abstract:

The novel axially dicarborane substituted silicon (IV) (SiPc-DC) phthalocyanine was synthesized by treating silicon phthalocyanine dichloride SiPc(Cl)2 (SiPc) with o-Carborane monool. The compound was characterized by mass spectrometry, UV-Vis, FT-IR, (1)H and (11)B Nuclear Magnetic Resonance Spectroscopy (NMR). Spectral, photophysical (fluorescence quantum yield) and photochemical (singlet oxygen (ΦΔ) and photodegradation quantum yield (Φd)) properties of the complex were reported in different solutions (Dimethyl sulfoxide (DMSO), Dimethylformamide (DMF) and Toluene). The results of spectral measurements showed that both SiPc and carborane cage can have potential to be used as sensitizers in photodynamic therapy (PDT) and boron neutron capture therapy (BNCT) by their singlet oxygen efficiencies (ΦΔ=0.41, 0.39).

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP19333109 Silicon phthalocyanine dichloride Silicon phthalocyanine dichloride 19333-10-9 Price
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